The following table lists some of the more commonly used medications during assisted reproductive treatment (ART). It is a guide only to the use of each medication and the minor related adverse effects. For further information, discuss with your Monash IVF Specialist and read the package inserts provided with each medication.

 

Glossary of Medications
Medication Adverse Effects
Clomiphene Citrate (Clomid)
A mild oral fertility medication that promotes development of ovarian follicles.
Hot flushes, mood swings, depression, abdominal discomfort and thick dry mucous.
Folic Acid
A vitamin taken prior to and during the first 12 weeks of pregnancy that may help to prevent spina bifida.
None reported.
Follicle Stimulating Hormone (FSH)
An injectable medication used to stimulate the development of ovarian follicles.
Mood swings and abdominal distension. Local irritation at injection site, stinging sensation at time of injection.
GnRH Agonist
A medication used to suppress hormone production in preparation for an IVF/ICSI or GIFT/MIFT cycle.
Reversible menopausal-type symptoms including tiredness, headaches and hot flushes.
GnRH Antagonist
A medication used to suppress spontaneous ovulation during and IVF/ICSI or GIFT/MIFT cycle.
Local irritation at injection site.
Human Chorionic Gonadotrophin (hCG) (“trigger medication”)
An injection used to “trigger” the final maturation of eggs prior to ovulation or egg collection
Stinging sensation at time of injection and local irritation at injection site. Possibility of increased abdominal distension.
Oestrogen Supplementation
Oestrogen tablets or patches to thicken the lining of the uterus, usually in preparation for embryo transfer.
Headaches.
Oral Contraceptive Pill (OCP)
A medication usually used to prevent a pregnancy, but is used in ART to help time the start of a treatment cycle. May also reduce the development of small ovarian cysts, which can delay the start of ovarian stimulation.
Mild stomach upset, breakthrough bleeding.
Progesterone Supplementation
Progesterone vaginal gel or pessary to help maintain the lining of the uterus in readiness for a potential pregnancy.
Possible local irritation, abdominal discomfort or (rarely) an allergic reaction.