Monash IVF Research and Education Foundation

Our research projects are divided into the following categories:

Is Fresh Best?

Freezing of all viable embryos during an IVF cycle, rather than transferring a fresh embryo, is being adopted in the clinic for multiple reasons, including to reduce the incidence of ovarian hyperstimulation syndrome (OHSS) and to improve birth outcomes for both mother and baby. However, there is concern pregnancy outcomes may be compromised utilising this

Continue reading ›

Incidence and Zygosity of Twin Births Following Transfers Using a Single Fresh or Frozen Embryo

Transferring a single blastocyst has been shown to significantly reduce multiple pregnancy rates and to increase the likelihood of delivering at term a single healthy baby. There is an acceptance that the incidence of monozygotic twin births is higher in the ART population compared with naturally conceived births. However, there are conflicting reports regarding treatment

Continue reading ›

Decisions About Confirmatory Prenatal Testing Following Preimplantation Genetic Diagnosis

Preimplantation genetic diagnosis (PGD) is the process of genetically screening an embryo for either the correct chromosome complement or a specific inherited disorder to selectively transfer the genetically desired embryos to establish a healthy pregnancy. All couples who have PGD at Monash IVF are recommended to have prenatal diagnosis in a pregnancy following PGD. Testing

Continue reading ›

Oocyte Vitrification: Ivf and Pregnancy Outcomes at Monash Ivf

The initial success rates for oocyte cryopreservation were low due to the fragility of oocytes and their vulnerability to cellular disruption, but new freezing methods have lead to better outcomes. Vitrification protocols use fast cooling rates combined with a higher concentration of cryoprotectant substances to prevent the formation of ice crystals within the oocytes. Ideally,

Continue reading ›