Monash IVF is proud to have leading IVF success rates. We are committed to providing the latest and most proven clinical treatment programs to help you achieve a successful pregnancy.
The following graph shows clinical pregnancy rates (a pregnancy confirmed by a blood test). Not all clinical pregnancies lead to a successful birth.
Blastocyst transfers have become the treatment of choice for the majority of patients at Monash IVF clinics. A blastocyst is formed after a fertilised egg (embryo) is cultured in the laboratory for five days. Culturing embryos identifies those embryos that have the best chance of forming a pregnancy. Recent publications of local and international data consistently show that the average patient will conceive more quickly following a blastocyst embryo transfer.
Extending the culture of embryos to five days requires a considerable investment in technology and expertise, but our commitment aims to reduce the number of cycles required for the birth of a healthy baby.
In 2009, two in three patients had a blastocyst transfer five days after egg collection.
Single Blastocyst Transfers
As the pregnancy rate following blastocyst transfer results in a higher pregnancy rate, it is strongly recommended that only one embryo is transferred to reduce the chance of twins or triplets. For these reasons, the majority of the embryo transfers performed at Monash IVF are single blastocyst transfers.
Important Factors to Consider when using Success Tables to Assess Clinics
In comparing success rates, many factors contribute to a clinic’s results. These factors include the range of Assisted Reproductive Technologies (ART) offered by the clinic and the criteria for allowing treatment. A clinic’s success rate may vary from year-to-year with the introduction of new reproductive technologies. However, the more cycles a clinic carries out, the less the rate is likely to vary.
Some clinics see more patients with difficult infertility problems, even though the probability of achieving success is low. Other clinics discourage such patients and only treat those with a high probability of achieving a pregnancy. At Monash IVF we treat all patients, even those who have been unsuccessful elsewhere.
Definition of Pregnancy: Monash IVF defines a pregnancy as evidence of a gestational sac on ultrasound scan at around 7 weeks’ gestation and not just a positive blood test.
Elective Single Embryo Transfer
More people are electing to have one embryo transferred to minimise their risk of a twin pregnancy. One in three of these patients achieve a pregnancy from these cycles and when subsequent frozen cycles are accounted for, the take home baby rate reaches over 50%.
If pregnancy does not result from the fresh embryo transfer and there have been embryos frozen for you, frozen embryo thawing and transfer is recommended before commencing another stimulated cycle. If donor gametes are involved, embryos from different donors, or partner and donor cannot be transferred together.
Embryos can be frozen from Day 1 to Day 7 after insemination. To be suitable for freezing, embryos must be dividing at the expected rate and have only a few fragments between the cells of the embryos. Experience has shown that embryos not meeting these criteria are highly unlikely to survive the freeze/thaw process. On average 2 out of 3 embryos available for freezing on day 3 are frozen and 1 out of 4 for day 5 – 6 freezing.
Similarly, approximately 2 out of 3 of the embryos frozen survive thawing in a condition that is suitable for transfer. Some people have tracking cycles for a frozen embryo transfer and because the embryos do not survive the thawing procedure, do not have a transfer.
Frozen Embryo Transfers
Recent advances in embryo freezing have enabled a substantial improvement in the pregnancy rates after the transfer of thawed embryos. These improvements have been largely due to the introduction of an embryo and oocyte freezing technique known as vitrification. This has resulted in improved embryo survival at thawing and an increase in the clinical pregnancy rate. These enhancements have allowed us to transfer single thawed embryos without compromising the pregnancy rates.
Will your Treatment be Successful?
Your Fertility Specialist will advise you as to your specific treatment options, and will also explain to you your chances of success, taking into consideration your type of infertility, your age and your treatment. ART procedures have progressed rapidly since their development and so have the associated success rates, but generalised success rates can be misleading due to the individuality of each patient’s situation. There are many hurdles to cross during treatment and it is recommended to keep in mind they all need to be successfully crossed in order to achieve a successful pregnancy.
Talk to your Fertility Specialist, IVF Nurse and Counsellor about these hurdles and your specific treatment, and ask as many questions as you need to. It is better to be well prepared than to have to deal with unexpected events during this important, and sometimes-difficult stage of your life.
Success rates can be affected by many factors, including:
- Genetic factors
- Fertility history
- Age of the female partner
- Lifestyle factors including weight and smoking
- Conditions contributing to infertility
- Quality of eggs and number of eggs recovered
- Quality of sperm (including motility and ability to penetrate the egg)
- Quality control in the laboratories; and
- Skill and competence of the treatment team
Although ART offers important options for the treatment of fertility problems, the decision to use ART involves many factors in addition to success rates. Going through repeated ART cycles requires substantial commitments of time, effort, money, and emotional energy. Therefore, you should carefully examine all related financial, psychological and medical issues, before beginning treatment. You may also wish to consider the location of the clinic, the counselling and support services available, and the rapport that staff have with their patients.
The pregnancy and birth rates for patients having routine IVF treatment decrease quite significantly from around 35 years of age.