The establishment of a normal range of embryonic heart rates in IVF pregnancies at seven weeks’ gestation in an Australian population: embryonic heart rate as a determinant of first trimester loss - | IVF Treatment | Monash IVF Australia

The establishment of a normal range of embryonic heart rates in IVF pregnancies at seven weeks’ gestation in an Australian population: embryonic heart rate as a determinant of first trimester loss

Investigators: Presanna Sujenthiran (1), Dr Martha Finn (1), Dr Simon Meagher (1), Paul Lombardo (2)

1 Monash Ultrasound for Women, Richmond; 2 Dept. Medical Imaging and Radiation Sciences, Monash University

ART births now account for ~3.6% of Australian births with almost 10,000 born each year. The 7 week ultrasound has become a definitive time to confirm a live intrauterine gestation for ART patients and it is therefore crucial to have established ultrasound parameters at this gestation. The boundary between normal and slow early embryonic heart rate (EHR) has not been well established in ART pregnancies. The study aims to establish a normal range of embryonic heart rates at 7 weeks gestation in ART singleton pregnancies as well as to analyse whether the EHR between 6W1D (i.e. 6 weeks and one day) and 7W6D in singleton ART pregnancies is useful in predicting the likelihood of first trimester loss. The range of EHRs will be evaluated to determine whether they form a normal distribution. The primary outcomes include successful first trimester pregnancy, confirmed by the standard 12 week ultrasound examination or miscarriage confirmed by ultrasound or medical documentation.

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