The effects of unrecognised Chlamydial infection on sperm production in human infertility - | IVF Treatment | Monash IVF Australia

The effects of unrecognised Chlamydial infection on sperm production in human infertility

Investigators: A/Prof Ken Beagley 1, Dr Danica Hickey 1, Emily Bryan 1, Prof Eileen MacLaughlin 2, Prof Rob McLachlan 3, A/Prof Luk Rombauts 3,4, Caroline Motteram 3, Dr Darren Katz 5

1 Queensland University of Technology, Brisbane; 2 University of Newcastle, Callaghan; 3 Monash IVF, Clayton; 4 Monash Dept Obstetrics and Gynaecology, Clayton; 5 The Centre for Specialist Men’s Health and Fertility, Melbourne.

Chlamydial infections are very common in our community with about 25% of people aged 25-35 yrs having past or current infections. Many people have no symptoms and therefore don’t receive treatment and as a result, chronic infections may occur that damages reproductive tissues in females and potentially in males. We now believe that Chlamydial infection of the testis can damage sperm production leading to infertility. The purpose of this research is to investigate whether male infertility can be caused by the sexually transmitted infection, Chlamydia. Testicular tissue obtained after testicular biopsy will be used to find out the effects of possible unrecognized infection on sperm development, and the ways this damage occurs. We hope to develop methods for early diagnosis of infections.

Recruitment for this clinical trial is ongoing and is offered to patients receiving treatment at our Clayton and Richmond clinics.

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